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KMID : 0614620130620040206
Korean Journal of Gastroenterology
2013 Volume.62 No. 4 p.206 ~ p.212
Is There a Difference in the Prevalence of Gastroesophageal Reflux Disease between Peritoneal Dialysis and Hemodialysis Patients?
Song Hyun-Jung

Kim Sun-Moon
Lee Yu-Mi
Hwang Jung-Ah
Moon Kyoung-Min
Moon Chang-Gi
Koo Hoon-Sup
Song Kyung-Ho
Kim Yong-Seok
Lee Tae-Hee
Huh Kyu-Chan
Choi Young-Woo
Kang Young-Woo
Hwang Won-Min
Yun Sung-Ro
Abstract
Background/Aims: Gastroesophageal reflux disease (GERD) is a common upper gastrointestinal disorder in patients with chronic kidney disease (CKD). However, little is known about the prevalence of GERD in dialysis patients. The aim of the present study was to investigate the difference in the prevalence of GERD in peritoneal dialysis and hemodialysis patients.

Methods: From July 2010 to August 2011, peritoneal dialysis patients (n=30) and hemodialysis patients (n=38) were enrolled. The prevalences of GERD were assessed at a single center with endoscopic findings and interviews using a questionnaire. Also, risk factors of GERD were evaluated.

Results: The prevalences of GERD in peritoneal dialysis and hemodialysis patients were 33.3% and 39.5% (p=0.748), respectively. The prevalences of erosive reflux esophagitis (ERD) in peritoneal dialysis and hemodialysis patients were 16.7% and 23.7% (p=0.477), respectively. The prevalences of nonerosive reflux disease (NERD) in peritoneal dialysis and hemodialysis patients were 16.7% and 13.2% (p=0.685), respectively. The prevalences of GERD, ERD and NERD were higher than those of the general population. The risk factor for GERD was age in hemodialysis patients.

Conclusions: The prevalence of GERD in dialysis patients was higher than that in the general population. However, there was no significant difference between peritoneal dialysis and hemodialysis patients.
KEYWORD
Gastro-esophageal reflux, Peritoneal dialysis, Renal dialysis, Chronic kidney failure
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